The Vulnerable Patient

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[From vulnerable plaque to vulnerable patient].

Atherosclerotic plaque instability is directly involved in triggering acute coronary syndromes, including unstable angina, acute myocardial infarction, and sudden coronary death. Different and not completely unknown mechanisms are involved in the pathogenesis of the destabilisation of the vulnerable plaque; currently three mechanisms are considered to play a causal role in this process: emboliz...

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The vulnerable patient: refocusing on the plaque?

The term 'vulnerable plaque' is used to refer to the lesions that are prone to rupture and may cause life-threatening events like acute coronary syndrome or stroke. The study of the vulnerable plaque phenotype and its detection has attracted increasing interest over the past decades. During this time, there have been some remarkable transitions in the paradigm on methods to identify patients at...

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The vulnerable microcirculation in the critically ill pediatric patient

In neonates, cardiovascular system development does not stop after the transition from intra-uterine to extra-uterine life and is not limited to the macrocirculation. The microcirculation (MC), which is essential for oxygen, nutrient, and drug delivery to tissues and cells, also develops. Developmental changes in the microcirculatory structure continue to occur during the initial weeks of life ...

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Vulnerable, but strong: The spinal cord-injured patient during rehabilitation

A traumatic spinal cord injury affects the body to an extent that the patient requires the assistance of others to survive and recover. The rehabilitation phase puts the patient in a vulnerable position and involves a considerable amount of strength on the patient's part. The aim of this paper is to explore the vulnerability of the spinal cord patient and how this vulnerability connects to the ...

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An Autistic Child: The Vulnerable Patient: A Case Report

AL is an 8-year old girl who presented with a 4-year history of impairments in all aspects of the autistic triad: social interaction, imagination, and social communication. Her teacher noticed a lack in the drive to explore environments and ability to ‘parallel play’, a developmental concept whereby infants begin to play alongside each other. However, a regression of verbal communication caused...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2015

ISSN: 0735-1097

DOI: 10.1016/j.jacc.2015.07.019